The BHLHA15 antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to BHLHA15. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The BHLHA15 antibody has been validated for the following applications: EIA, Immunoassay, Precipitation, ELISA, Immunoprecipitation, and Western Blot.
Description
Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'(By similarity)